2020年

序号 发表时间 论文名称 作者 刊物、出版社名称 卷、期（或章节）、页 1 2020-01 Palladium-Catalyzed   Asymmetric [4+3] Cyclization of Trimethylenemethane: Regio-, Diastereo-, and   Enantioselective Construction of Benzofuro[3,2-b]azepine Skeletons Liu   Yang-Zi, Wang Zhongao, Huang Zesheng, Zheng Xing, Yang Wu-Lin*, and Deng   Wei-Ping* Angew.   Chem. Int. Ed. 2020, 59, 1238-1242 2 2020-07 An   Artemisinin‐Derivative–(NHC)Gold(I)   Hybrid with Enhanced Cytotoxicity through Inhibition of NRF2 Transcriptional   Activity Chen   Zhang, Pierre-Yves Fortin, Guillaume Barnoin, Xue Qin  , Xing Wang, Alvaro Fernandez Alvarez,   Christian Bijani, Marie-Lise Maddelein, Catherine Hemmert*, Olivier   Cuvillier*  , Heinz Gornitzka* Angew.Chem.   Int. Ed. 2020,   59, 12062-12068 3 2020-07 Ribosomal   S6 protein kinase 4 promotes radioresistance in esophageal squamous cell   carcinoma. Mingyang   Li, Linni Fan, Donghui Han, Zhou Yu, Jing Ma, Yixiong Liu, Peifeng Li, Danhui   Zhao, Jia Chai, Lei Jiang, Shiliang Li, Juanjuan Xiao, Qiuhong Duan, Jing Ye,   Mei Shi, Yongzhan Nie, Kai-Chun Wu, Dezhong Joshua Liao, Yu Shi, Yan Wang,   Qingguo Yan, Shuangping Guo, Xiu-Wu Bian, Feng Zhu, Jian Zhang, Zhe Wang. J.   Clin. Invest. 2020,   130(8), 4301-4319 4 2020-04 A   single-component light sensor system allows highly tunable and direct   activation of gene expression in bacterial cells Xie   Li, Changcheng Zhang, Xiaopei Xu, Jun Miao, Jing Yao, Renmei Liu, Yuzheng   Zhao, Xianjun Chen,* and Yi Yang,* Nucleic   Acids Res. 2020,   48(6), e33 5 2020-07 Novel   and potent inhibitors targeting DHODH, a rate-limiting  enzyme in de novo pyrimidine biosynthesis,   are broad-spectrum antiviral against RNA viruses including newly emerged   coronavirus SARS-CoV-2 Rui   Xiong, Leike Zhang, Shiliang Li, Yuan Sun, Minyi Ding, Yong Wang, Yongliang   Zhao, Yan Wu, Weijuan Shang, Xiaming Jiang, Jiwei Shan, Zihao Shen, Yi Tong,   Liuxin Xu, Yu Chen, Yingle Liu, Gang Zou, Dimitri Lavillete, Zhenjiang Zhao,   Rui Wang, Lili Zhu, Gengfu Xiao, Ke Lan, Honglin Li*, Ke Xu* Protein   Cell. 2020, 11, 723–739 6 2020-04 Illuminating   NAD(+) Metabolism in Live Cells and In Vivo Using a Genetically Encoded   Fluorescent Sensor Yejun   Zou, Aoxue Wang, Li Huang, Xudong Zhu, Qingxun Hu, Yinan Zhang, Xianjun   Chen,  Fengwen Li, Qiaohui Wang, Hu   Wang, Renmei Liu, Fangting Zuo, Ting Li, Jing Yao, Yajie Qian, Mei Shi, Xiao   Yue, Weicai Chen, Zhuo Zhang, Congrong Wang, Yong Zhou, Linyong Zhu, Zhenyu   Ju, Joseph Loscalzo, Yi Yang,* and Yuzheng Zhao* Dev.   Cell 2020,   53, 1-13 7 2020-06 First-generation   species-selective chemical probes for fluorescence imaging of human   senescence-associated β-galactosidase. Xiaokang   Li#, Wenjing Qiu#, Jinwen Li#, Xi Chen#, Yulu Hu, Ying Gao,   Donglei Shi, Xinming Li, Huiling Lin, Zelan Hu, Guoqiang Dong, Chunquan   Sheng, Bei Jiang, Conglong Xia, Chu-Young Kim, Yuan Guo*, Jian Li*. Chem.   Sci. 2020,   11, 7292–7301 8 2020-05 A   self-immobilizing near-infrared fluorogenic probe for sensitive imaging of   extracellular enzyme activity in vivo Yuyao   Li, Heng Song, Chenghong Xue, Zhijun Fang, Liqin Xiong, and Hexin Xie* Chem.   Sci. 2020,   11, 5889-5894 9 2020-01 Targeting   virulence factors as an antimicrobial approach: Pigment inhibitors.  Shuaishuai   Ni#, Baoli Li#, Yixiang Xu#, Fei Mao, Xiaokang Li,   Lefu Lan, Jin Zhu, Jian Li*. Med.   Res. Rev.  2020,   40, 293-338 10 2020-01 Spatiotemporally   controllable diphtheria toxin      expression using a light-switchable transgene system combining   multifunctional nanoparticle delivery system for targeted melanoma therapy He,   Muye, Wang, Yan, Chen, Xianjun, Zhao, Yuzheng, Lou, Kaiyan, Wang, Yujie,   Huang, Lei, Hou, Xinyu, Xu, Jiajun, Cai, Xiaoran, Cheng, Yi, Lan, Minbo,   Yang, Yi*, Gao, Feng* J.   Control. Release 2020, 319, 1-14 11 2020-05 Lysosomal   polarity increases with aging as revealed by a lysosome-targetable   near-infrared fluorescent probe. Donglei   Shi#, Linghao Hu#, Xinming Li#, Wenwen Liu, Ying Gao,   Xiaokang Li, Bei Jiang, Conglong Xia, Yuan Guo*, Jian Li*. Sensor.   Actuator. B-Chem. 2020,   319, 128302. 12 2020-10 Sensitive   detection via the time-resolved fluorescence of circularly permuted yellow   fluorescent protein biosensors Lei   Li, Yuchi Cheng, Shiyu Shen, Jiasheng Zhou, Aoxue Wang, Guoqing Chen, Jianhua   Xua, Yi Yang, Yuzheng Zhao*, Sanjun Zhang*, Yang Tian Sensor.   Actuat. B-Chem. 2020,   321, 128614 13 2020-3 Repurposing   antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent. Hongxuan   Feng#, Linghao Hu#, Hongwen Zhu#, Lingxue Tao#, Lei Wu, Qinyuan Zhao,   Yemi Gao, Qi Gong, Fei Mao, Xiaokang Li, Hu Zhou*, Jian Li*, Haiyan Zhang*. Acta   Pharm. Sin. B  2020,   10, 434–446 14 2020-1 Discovery   of nitazoxanide-based derivatives as autophagy activators for the treatment   of Alzheimer's disease. Xiaokang   Li#, Jian Lu#, Yixiang Xu#, Jiaying Wang, Xiaoxia   Qiu, Lei Fan, Baoli Li, Wenwen Liu, Fei Mao, Jin Zhu, Xu Shen*, Jian Li*. Acta   Pharm. Sin. B  2020,   10, 646-666. 15 2020.04 A   combination of LightOn gene expression system and tumor   microenvironment-responsive nanoparticle delivery system for targeted breast   cancer therapy Xinyu   Hou, Chenting Shou, Muye He, Jiajun Xu, Yi Cheng, Zeting Yuan, Minbo Lan,   Yuzheng Zhao, Yi Yang, Xianjun Chen*, Feng Gao* Acta   Pharm. Sin. B  2020, 10(9),   1741-1753 16 2020-06 Lighting   Up Live-Cell and In Vivo Central Carbon Metabolism with Genetically Encoded   Fluorescent Sensors Zhuo   Zhang, Xiawei Cheng, Yuzheng Zhao*, and Yi Yang* Annu.   Rev. Anal. Chem. 2020,   13(1), 293-314 17 2020.03 Multiple   targeting strategies achieve novel protein drug deliver into cancer cells to   proapoptosis lung cancer cell by precisely inhibiting surviving.  Fabiao   Hu,Ting Yan, Wei Guo, Qiuli Liu, Myong Hun Han, Chang Liu,Yuping Liu, Wenyun   Zheng*,  Fang You*, Yi Yang, Wenliang   Zhang and Xingyuan Ma* Nanoscale 2020,   12, 10623-10638 18 Oct-20 Fluorophore-Promoted   Facile Deprotonation and Exocyclic Five-Membered Ring Cyclization for   Selective and Dynamic Tracking of Labile Glyoxals Huan   Xu, Qianqian Liu, Xiaodong Song, Chao Wang, Xinru Wang, Shengnan Ma, Xiaolei   Wang, Yan Feng, Xiangming Meng, Xiaogang Liu,* Wei Wang,* and Kaiyan Lou* Anal.   Chem. 2020,   92, 13829-13838 19 Jul-05 In   vivo Visualization of γ-Glutamyl transpeptidase Activity with an Activatable   Self-immobilizing Near-Infrared Probe Yuyao   Li, Chenghong Xue, Zhijun Fang, Weipan Xu, and Hexin Xie* Anal.   Chem. 2020,   92, 15017-15024 20 2020-04 Elaboration   of phosphoramidite ligands enabling palladiumcatalyzed diastereo- and   enantioselective all carbon [4+3] cycloaddition Zheng   Xing, Sun Hao, Yang Wu-Lin*, Deng Wei-Ping*. Sci.   Chin. Chem. 2020, 63, 911-916 21 2020-11 Photodynamic   therapy induces autophagymediated cell death in human colorectal cancer cells   via activation of the ROS/JNK signaling pathway Changfeng   Song, Wen Xu, Hongkun Wu, Xiaotong Wang, Qianyi Gong, Chang Liu, Jianwen Liu*   and Lin Zhou* Cell   Death Dis. 2020,  11, 938-952 22 2020-02 A   novel multistage antiplasmodial inhibitor targeting Plasmodium   falciparum histone deacetylase.  Zhenghui   Huang#,*, Ruoxi Li#, Tongke Tang#, Dazheng Ling#, Manjiong Wang#, Dandan Xu#, Maoxin Sun, Lulu   Zheng, Feng Zhu, Hui Min, Rachasak Boonhok, Yan Ding, Yuhao Wen, Yicong Chen,   Xiaokang Li, Yuxi Chen, Taiping Liu, Jiping Han, Jun Miao, Qiang Fang, Yaming   Cao, Yun Tang, Jie Cui, Wenyue Xu, Liwang Cui, Jin Zhu, Gary Wong, Jian Li*,   Lubin Jiang*. Cell   Discov. 2020,   6, 93 23 2020-05 Identification   of the new covalent allosteric binding site of FBPase with disulfiram   derivatives toward glucose reduction. Yunyuan   Huang#, Yixiang Xu#, Rongrong Song#, Shuaishuai Ni#, Jiaqi Liu, Yanhong   Xu, Yanliang Ren*, Li Rao, Yingjie Wang, Lin Wei, Lingling Feng, Chen Su,   Chao Peng, Jian Li*, Jian Wan*. J.   Med. Chem. 2020,   63, 6238–6247. 24 2020-01 Development   of novel N-hydroxypyridone   derivatives as potential anti-ischemic stroke agents Linghao   Hu#, Hong-Xuan   Feng#,   Hongguang Zhang, Songda Yu, Qinyuan Zhao, Wei Wang, Fengxia Bao, Xun Ding,   Jiajing Hu, Manjiong Wang, Yixiang Xu, Zengrui Wu, Xiaokang Li, Yun Tang, Fei   Mao*, Xiaoyan Chen, Haiyan Zhang*, Jian Li*. J.   Med. Chem. 2020,   63, 1051-1067 25 2020-06 Catalytic   Asymmetric [3+2] Annulation via Indolyl Copper-Allenylidene Intermediates:   Diastereo- and Enantioselective Assembly of Pyrrolo[-a]indoles Zhang   Jian, Ni Tao, Yang Wu-Lin*, Deng Wei-Ping* Org.   Lett. 2020, 22, 4547-4552 26 2020-05 Organocatalytic   Regiodivergent Ring Expansion of Cyclobutanones for the Enantioselective   Synthesis of Azepino[ a]indoles and Cyclohepta[b]indoles Yang   Wu-Lin*, Li Wen, Yang Zhong-Tao, Deng Wei-Ping* Org.   Lett. 2020, 22, 4026-4032 27 2020-2 Dimethylformamide-Modulated   Kdo Glycosylation for Stereoselective Synthesis of α‑Kdo Glycosides. Qixin   Lou, Qingting Hua, Liangliang Zhang, and You Yang* Org.   Lett. 2020,   22(3), 981-985 28 2020-10 Synthesis   of l-glycero- and d-glycero-d-manno-Heptose Building Blocks for   Stereoselective Assembly of the Lipopolysaccharide Core Trisaccharide of Vibrio parahemolyticus O2. Junchang   Wang, Jingjing Rong, Qixin Lou, Yirong Zhu, and You Yang* Org.   Lett. 2020,   22(20), 8018-8022 29 2020-11 Total   Synthesis and Immunological Evaluation of the Tri-d-glycero-d-manno-heptose   Antigen of the Lipopolysaccharide as a Vaccine Candidate against Helicobacter pylori. Junchang   Wang,§ Yiyue Zhang,§ Yirong Zhu, Junru Liu, Yan Chen, Xin Cao, and You Yang* Org.   Lett. 2020,   22(22), 8780-8785 30 Aug-20 Enantioselective   [4 + 2] Cycloaddition Reaction of Vinylquinolines with Dienals Enabled by   Synergistic Organocatalysis Jing   Chen, Yiwei Fu, Yang Yu, Jian-Rong Wang, Yue-Wei Guo,* Hao Li,* and Wei Wang* Org.   Lett.  2020,   22, 6061-6066 31 2020-10 Transition-Metal   Free Chemoselective Hydroxylation and Hydroxylation–Deuteration of   Heterobenzylic Methylenes Yonghai   Liu, Yang Yu, Chengyu Sun, Yiwei Fu, Zhiguo Mang, Lei Shi, and Hao Li* Org.   Lett.  2020,   22, 8127–8131 32 Jan-20 A   cascade approach to 3D cyclic carbamates via an ionic decarboxylative   functionalization of olefinic oxamic acids Huaqiang   Fan,‡ Yi Wan,‡ Peng Pan, Wenbin Cai, Shihui Liu, Chuanxu Liu* and Yongqiang   Zhang * Chem.   Commun. 2020,   56, 86-89 33 2020-6 Loss   of thioredoxin reductase function in a mouse stroke model disclosed by a   two-photon fluorescent probe Jintao   Zhao, Yuan Qu, Hao Gao, Miao Zhong,    Xinming Li,  Fang Zhang, Yaxiong   Chen, Lu Gan,  Guodong Hu, Hong Zhang,  Shengxiang Zhang*  and    Jianguo Fang * Chem.   Commun. 2020,56,   14075-14078 34 2020-2 Structure-guided   engineering of Pseudomonas dacunhael-aspartate β-decarboxylase for   l-homophenylalanine synthesis Min   Zhang,  Pengfei Hu,  Yu-Cong Zheng,  Bu-Bing Zeng,   Qi Chen,    Zhi-Jun Zhang*  and  Jian-He Xu*   Chem.   Commun. 2020,56,   13876-13879 35 Jul-05 A   novel method combining aptamer-Ag10NPs based microfluidic biochip with bright   field imaging for detection of KPC-2-expressing bacteria Jing   Chen, Hui Li, Hexin Xie*, Danke Xu* Anal.   Chim. Acta. 2020,   1132，20-27 36 2020-10 Kinetic   resolution of 2H-azirines via Cu(I)-catalyzed asymmetric 1,3-dipolar   cycloaddition of azomethine ylides. Deng   Hua, Liu Tian-Tian, Ding Zheng-Dong, Yang Wu-Lin, Luo Xiaoyan*, Deng   Wei-Ping* Org.   Chem. Front. 2020, 7(20),   3247-3252 37 2020-3 Copper(i)-catalyzed   asymmetric [3 + 3] annulation involving aziridines to construct   tetrahydro-β-carbolines Chao   Ye  Wu-Lin Yang, Yufei Zhai,  Hua   Deng,  Xiaoyan Luo*   Guoyin   Kai*  and  Wei-Ping Deng Org.   Chem. Front. 2020,   7, 3393-3398 38 Sep-20 Graphitic   Carbon Nitride Polymer as a Recyclable Photoredox Catalyst for   Decarboxylative Alkynylation of Carboxylic Acids Jiaqi   Guo, Yating Wang, Yuhang Li, Kailin Lu, Shihui Liu, Wei Wang* and Yongqiang   Zhang,* Adv.   Synth. Catal. 2020,   362, 2620-2625 39 Jul-20 Aldehydes   Switch Regioselectivity: a Prins Cyclization Strategy for the Synthesis of   Indoline-fused THFs and Indole-fused Oxepanes Xiaobei   Chen, Yuanrui Jiang, Huihui Geng, Xingyu Liu, Yizhuo Huang, Jingwei Lu,   Chenjing Gao, Shilei Zhang,* Jian Zhang,* and Wei Wang* Adv.   Synth. Catal. 2020,   362, 2620– 2625 40 2020-04 Targeting   CD133 reverses drug-resistance via the AKT/NF-κB/MDR1 pathway in colorectal   cancer.  Zeting   Yuan1, Xin Liang1, Yueping Zhan1, Ziyuan Wang, Jian Xu, Yanyan Qiu, Jie Wang,   Yijun Cao, Van-Minh Le, Hai-Trieu Ly, Jianhua Xu, Wei Li*, Peihao Yin*, Ke   Xu*.  Br.   J. Cancer.  2020, 122(9),   1342-1353. 41 2020-7 Development   of disulfide-derived fructose-1,6-bisphosphatase (FBPase) covalent inhibitors   for the treatment of type 2 diabetes. Yi-xiang   Xu#, Yun-yuan   Huang#,   Rong-rong Song#, Yan-liang Ren, Xin Chen, Chao Zhang, Fei Mao, Xiao-kang Li,   Jin Zhu, Shuai-shuai Ni*, Jian Wan*, Jian Li*.  Eur. J. Med. Chem.  2020, 203, 112500 42 Feb-20  Design, synthesis and evaluation of   diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease   agents Guixiang   Yang, Yan Huang, Lulu Zheng, Li Zhang, Lin Su, Yuhang Wu, Jie Li, Licheng   Zhou, Jin Huang, Yun Tang*, Rui Wang*, Lei Ma* Eur.   J. Med. Chem. 2020,   187, 111913 43 2020-05 Mesenchymal   stem cells combined with Liraglutide relieve acute lung injury through   apoptotic signaling restrained by PKA/β-catenin. Xiaotong   Yang, Xiaoying Ma, Ocholi Don, Yuanlin Song, Xiaoyan Chen, Jianwen Liu*,   Jieming Qu* and Yun Feng* Stem   Cell Res. Ther. 2020, 11, 182-198 44 2020-2 A   Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a   Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies Saixu   Huang,# Zhiyong Huang,# Zhiqin Fu,# Yamin Shi,, Qi   Dai, Shuyan Tang, Yongwei Gu, Youfa Xu, Jianming   Chen,, Xin Wu, and Fuzheng Ren* Int.   J. Nanomed. 2020,   15, 1161-1172 45 2020-01 In silico prediction of binding   capacity and interaction forces of organic compounds with alpha- and   beta-cyclodextrins Peiwen   Di, Jianhui Chen, Liping Liu, Weihua Li, Yun Tang*, Guixia Liu* J.   Mol. Liq. 2020,   302, 112585 46 2020-01 Discovery   and biological evaluation of   N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide   as potent Bruton’s tyrosine kinase inhibitors Meng-zhen   Lai, Pei-ran Song, Dou Dou, Yan-yan Diao, Lin-jiang Tong, Tao Zhang, Hua   Xie*, Hong-lin Li*, Jian Ding* Acta   Pharmacol. Sin. 2020, 41, 415-422 47 2020-04 Natural   Product Piperine Alleviates Experimental Allergic Encephalomyelitis in Mice   by Targeting Dihydroorotate Dehydrogenase Zehui   Liu, Qian Hu1,Wanyan Wang, Sisi Lu, Dang Wu, Shuyin Ze,      Jiacheng He, Ying Huang, Wuyan Chen, Yechun Xu,Weiqiang Lu*, Jin      Huang* Biochem.   Pharmacol. 2020,   177, 114000 48 2020-2 Mechanistic   Insights into the Regio- and Stereoselectivities of Testosterone and   Dihydrotestosterone Hydroxylation Catalyzed      by CYP3A4 and CYP19A1 Junhao   Li, Yun Tang, Weihua Li,* and Yaoquan Tu* Chem.   Eur. J.  2020, 26, 6214-6223 49 2020-08 PTBP3   Induced Inhibition of Differentiation of Gastric Cancer Cells Through   Alternative Splicing of Id1.  Bin   Chen, Weixia Chen, Xiaoyan Mu, Liyan Yang, Xiangyu Gu, Aiguang Zhao*, Xin   Liang*, Jianwen Liu*.  Front.   Oncol.  2020, 10, 1477 50 2020-3 Verapamil   extends lifespan in Caenorhabditis elegans by inhibiting calcineurin activity   and promoting autophagy. Wenwen   Liu#, Huiling Lin#, Zhifan Mao#, Lanxin Zhang, Keting   Bao, Bei Jiang, Conglong Xia, Wenjun Li, Zelan Hu*, Jian Li*. Aging-US  2020, 12, 5300–5317 51 2020-05 Diastereoselective   Synthesis of Functionalized Tetrahydro-γ-Carbolines via a [3+3] Cycloaddition   of 2,2'-Diester Aziridines with β-(Indol-2-yl)-α,β-unsaturated Ketones Zou   Xuejie, Liu Yangzi, Shang Shaojing, Yang Wulin*, Deng Wei-Ping* Chin.   Chem. Lett. 2020, 31, 1293-1296 52 2020-1 Discovery   of synergistic activity of fluoroquinolones in combination with antimicrobial   peptides against clinical polymyxin-resistant Pseudomonas   aeruginosa DK2. Xinyu   Zheng, Qiao Cao, Qin Cao, Fei Mao, Xiaokang Li, Jin Zhu*, Lefu Lan*, Jian Li*. Chin.   Chem. Lett. 2020,   31, 413–417 53 2020-6 A   rapid-response near-infrared fluorescent probe with a large Stokes shift for   senescence-associated β-alactosidase activity detection and imaging of   senescent cells. Wenjing   Qiu#, Xiaokang Li#, Donglei Shi, Xinming   Li, Ying Gao, Jinwen Li, Fei Mao, Yuan Guo, Jian Li*. Dyes   Pigments 2020,   182, 108657 54 2020-2 Curcumin-based   polarity fluorescent probes: Design strategy and biological applications. Linghao   Hu#, Donglei Shi#, Xinming Li#, Jin Zhu, Fei Mao,   Xiaokang Li, Conglong Xia, Bei Jiang, Yuan Guo*, Jian Li*. Dyes   Pigments  2020, 177, 108320 55 2020-02 Discovery   of a natural fluorescent probe targeting the Plasmodium falciparum cysteine   protease falcipain-2 Lili   Zhu, Lei Shan, Junsheng Zhu, Li Li, Shiliang Li, Liyan Wang, Jiawei Wang,   Shoude Zhang, Hongchang Zhou, Weidong Zhang*, Honglin Li* Sci.   China Life Sci. 2020, 63(7),   1016-1025 56 2020-06 Computational   insights into molecular activation and positive cooperative mechanisms of   FFAR1 modulators Dan   Teng, Jianhui Chen, Dongping Li, Zengrui Wu, Weihua Li, Yun Tang*, Guixia   Liu* J.   Chem. Inf. Model. 2020,   60, 3214-3230 57 2020-08 NetInfer:   a web server for prediction of targets, therapeutic and adverse effects via   network-based inference methods. Zengrui   Wu, Yayuan Peng, Zhuohang Yu, Weihua Li, Guixia Liu, and Yun Tang* J. Chem. Inf. Model. 2020, 60(8),   3687-3691 58 2020-8 Dissecting   the Structural Plasticity and Dynamics of Cytochrome P450 2B4 by Molecular   Dynamics Simulations Junhao   Li, Yang Zhou, Yun Tang, Weihua Li,* and Yaoquan Tu* J.   Chem. Inf. Model.  2020,   60, 5026-5035 59 2020-2 Computational   Insight into the Allosteric Activation Mechanism of Farnesoid X Receptor Yue   Chen, Junhao Li, Zengrui Wu, Guixia Liu, Honglin Li, Yun Tang,* and Weihua   Li* J.   Chem. Inf. Model.  2020,   60, 1540-1550 60 2020-4 Copper   Promoted Aerobic Oxidative C(sp3)–C(sp3) Bond Cleavage of   N-(2-(Pyridin-2-yl)-ethyl)anilines  Yang Yu, Yong Zhang, Chengyu Sun, Lei Shi,   Wei Wang*, and Hao Li* J.   Org. Chem.  2020,   85, 2725-2732 61 2020.01 Safe   and Efficacious Diphtheria Toxin-Based Treatment for Melanoma: Combination of   a Light-On Gene-Expression System and Nanotechnology Xu,   Jiajun, He, Muye, Hou, Xinyu, Wang, Yan, Shou, Chenting, Cai, Xiaoran, Yuan,   Zeting, Yin, Yu, Lan, Minbo, Lou, Kaiyan, Zhao, Yuzheng, Yang, Yi, Chen,   Xianjun*, Gao, Feng* Mol.   Pharmaceut. 2020, 17(1), 301-315 62 2020-01 Deep   Learning Based Drug Metabolites Prediction. Disha   Wang, Wenjun Liu, Zihao Shen, Lei Jiang, Jie Wang, Shiliang Li*, Honglin Li* Front.   Pharmacol. 2020, 10, 1586 63 2020-4 Drug–Drug   Cocrystals Provide Significant Improvements of Drug Properties in Treatment   with Progesterone Chunyang   Guo, Qi Zhang, Bingqing Zhu, Zaiyong Zhang, Xiaoyu Ma, Wenjuan Dai, Xiaoyi   Gong, Guobin Ren*, and Xuefeng Mei* Cryst.   Growth Des.  2020,   20, 3053-3063 64 2020-10 Pharmaceutical   Cocrystals of Nicorandil with Enhanced Chemical Stability and Sustained   Release Chunyang   Guo, Qi Zhang, Bingqing Zhu, Zaiyong Zhang, Junjie Bao, Qiaoce Ding, Guobin   Ren*, and Xuefeng Mei* Cryst.   Growth Des.  2020,   20, 6995-7005 65 2020-10 Strategy   for efficient discovery of cocrystals via a network-based recommendation   model. Lulu   Zheng,# Bin Zhu,# Zengrui Wu, Xiaoxue Fang, Minghuang Hong, Guixia Liu,   Weihua Li, Guobin Ren,* and Yun Tang* Cryst. Growth   Des.  2020, 20(10),   6820-6830. 66 2020-07 Shikonin   is a novel and selective IMPDH2 inhibitor that target triple-negative breast   cancer Wanyan   Wang, YuWu, Si Chen, Xi Liu, Jiacheng He, Shuyi Wang, Weiqiang Lu*, Yong   Tang*, Jin Huang* Phytother.   Res. 2020,   35(1), 463-476 67 2020-6 Quercetin   inhibits virulence properties of Porphyromas gingivalis in periodontal   disease Zhiyan   He, Xu Zhang, Zhongchen Song, Lu Li, Haishuang Chang, Shiliang Li* & Wei   Zhou* Scientifc   Reports 2020,   10, 18313 68 2020-09  Highly Regio-, Diastereo-, and   Enantioselective Assembly of Azepino[2,3 b]indoles via Palladium-Catalyzed   [4+3] Cycloaddition. Yang   Wu-Lin, Huang Zesheng, Liu Yang-Zi, Yu Xingxin*, Deng Wei-Ping* Chin.   J. Chem. 2020, 38(12),   1571-1574. 69 2020-05 Catalytic   Enantioselective Formal Synthesis of MDM2 Antagonist RG7388 and Its Analogue Zou   Xue-Jie, Yang Wu-Lin*, Zhu Jing-Yan, Deng Wei-Ping* Chin.   J. Chem. 2020, 38(5), 435-438 70 2020-09 Insights   into the interaction mechanisms of estrogen-related receptor alpha (ERR   alpha) with ligands via molecular dynamics simulations Dongping   Li, Yingchun Cai, Dan Teng, Zengrui Wu, Weihua Li, Yun Tang*, Guxia Liu* J.   Biomol. Struct. Dyn. 2020,   38, 3867-3878 71 2020-6 Discovery   of novel and highly selective PI3Kδ inhibitors based on the p110δ crystal   structure Wen-Qing   Jia,Ya-Ya Liu,Xiao-Yan Feng,Wei-Ren Xu &Xian-Chao Cheng* J.   Biomol. Struct. Dyn. 2020,   38, 2499-2508 72 2020-2 Virtual   identification of novel peroxisome proliferator-activated receptor (PPAR) α/δ   dual antagonist by 3D-QSAR, molecule docking, and molecule dynamics   simulation Ya-Ya   Liu,Ting-Ting Ding,Xiao-Yan Feng,Wei-Ren Xu &Xian-Chao Cheng*  J.   Biomol. Struct. Dyn. 2020,   38, 4143-4161 73 2020-2 Virtual   identification of novel PPARα/γ dual agonists by 3D-QSAR, molecule docking   and molecular dynamics studies Ya-Ya   Liu,Xiao-Yan Feng,Wen-Qing Jia,Zhi Jing,Wei-Ren Xu &Xian-Chao Cheng* J.   Biomol. Struct. Dyn. 2020,   38, 2672-2685 74 2020-8 Characterization   and rational design for substrate specificity of a prolyl endopeptidase from   Stenotrophomonas maltophilia Junjie   Yu, Junjie Wu, Dewei Xie, Lei Du, Ya-Jie Tang, Jingli Xie* Dongzhi Wei* Enzyme   Micro. Tech. 2020,   138, 109548 75 Jul-05 A   minor structure modification serendipitously leads to a highly   carbapenemase-specific fluorogenic probe Jie   Wang,‡ Weipan Xu,‡ Shuyuan Xue, Tao Yu and Hexin Xie* Org.   Biomol. Chem. 2020,   18, 4029-4033 76 2020-10 Synthesis   and Immunomodulatory Activity of the Sulfated Tetrasaccharide Motif of Type B   Ulvanobiuronic Acid 3-Sulfate. 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