2019年

序号 发表时间 论文名称 作者 刊物、出版社名称 卷、期（或章节）、页 1 2019-02 Ultra-large   library docking for discovering new chemotypes Jiankun   Lyu, Sheng Wang, Trent E. Balius, Isha Singh, Anat Levit1 , Yurii S. Moroz,   Matthew J. O’Meara , Tao Che, Enkhjargal Algaa , Kateryna Tolmachova , Andrey   A. Tolmachev , Brian K. Shoichet*, Bryan L. Roth* & John J. Irwin* Nature 2019,   566, 224-229 2 2019-09 Enantioselective   Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines:   Efficient Synthesis of Cipargamin Jinbin   Zhu, Linwei Huang, Wei Dong, Naikai Li,     Xingxin Yu, Weiping Deng*, Wenjun Tang* Angew.   Chem. 2019,   131,16265–16269 3 2019-05 Electrochemical   [4+2] Annulation-Rearrangement-Aromatizationof Styrenes: Synthesis of   Naphthalene Derivatives Yueyue   Ma, Jufeng Lv,Chengyu Liu, Xiantong Yao, Guoming Yan, WeiYu, and Jinxing Ye* Angew.   Chem. 2019,   131,6828-6832 4 2019-08 Light-Driven   Intramolecular C@NCross-Coupling via aLong-Lived PhotoactivePhotoisomer   Complex  Dong   Jing, Cong Lu, Zhuo Chen, Songyang Jin, Lijuan Xie, Ziyi Meng, Zhishan Su and   Ke Zheng* Angew.   Chem. 2019,   131,14808-14814 5 2019-09 Direct   Arylation of a-Amino C(sp3)-H Bonds by Convergent Paired Electrolysis  Yueyue   Ma, Xiantong Yao, Lei Zhang,Pufan Ni, Ruihua Cheng,and Jinxing Ye* Angew.   Chem. 2019,   131,16700-16704 6 2019-01 A   diversity-oriented rhodamine library for wide-spectrum bactericidal agents   with low inducible resistance against resistant pathogens Xiao   Luo, Liujia Qian, Yansheng Xiao, Yao Tang, Yang Zhao, Xia Wang, Luyan Gu,   Zuhai Lei, Jianming Bao, Jiahui Wu, Tingting He, Fupin Hu, Jing Zheng,   Honglin Li, Weiping Zhu, Lei Shao, Xiaojing Dong, Daijie Chen*, Xuhong Qian*,   Youjun Yang* Nat.   Commun. 2019,   10(1), 258 7 2019-08 A   genome-wide positioning systems network algorithm for in silico drug   repurposing Feixiong   Cheng, Weiqiang Lu, Chuang Liu, Jiansong Fang, Yuan Hou, Diane E. Handy,   Ruisheng Wang, Yuzheng Zhao, Yi Yang, Jin Huang, David E. Hill, Marc Vidal, Charis Eng & Joseph Loscalzo Nat.   Commun.  2019,   10, 3476 8 2019-02 Microbe-focused   glycan array screening platform Geissner,   A., Reinhardt, A., Rademacher, C., Johannssen, T., Monteiro, J., Lepenies,   B., Thepaut, M., Fieschi, F., Mrazkova, J., Wimmerova, M., Schuhmacher, F.,   Götze, S., Grünstein, D., Guo, X., Hahm, H. S., Kandasamy, J., Leonori, D.,   Martin, C. E., Parameswarappa, S. G., Pasari, S., Schlegel, M. K., Tanaka,   H., Xiao, G., Yang, Y., Pereira, C. L., Anish, C., Seeberger, P. H.* Proc.   Natl. Acad. Sci. USA 2019,   116(6), 1958-1967 9 2019-04 Photocatalytic   C–H silylation of heteroarenes by using trialkylhydrosilanes Shihui   Liu, Peng Pan, Huaqiang Fan, Hao Li,    Wei Wang* and Yongqiang Zhang* Chem.   Sci. 2019,   10, 3817-3825 10 2019-10 Predicting   physical stability of solid dispersions by machine learning techniques Run   Han, Hui Xiong, Zhuyifan Ye, Yilong Yang, Tianhe Huang, Qiufang Jing, Jiahong   Lu, Hao Pan, Fuzheng Ren*, Defang Ouyang* J.   Control. Release  2019, 311-312, 16-25 11 2019-10 Solvatochromism   and mechanochromism observed in a triphenylamine derivative Chunyang   Guo, Qi Zhang, Bingqing Zhu, Bin Zhu, Weiqun Zhou*, Guobin Ren*, Xuefeng Mei* Acta   Cryst. B 75:   839-844 12 2019-01 Trideuteromethylation   Enabled by a Sulfoxonium Metathesis Reaction Zuyuan   Shen, Shilei Zhang, Huihui Geng, Jiarui Wang, Xinyu Zhang, Anqi Zhou, Cheng   Yao, Xiaobei Chen* and Wei Wang* Org.   Lett. 2019,   21, 448-452 13 2019-02 Construction   of N‑Alkyl- and N‑Arylaziridines from Unprotected Amines via C−H Oxidative   Amination Strategy Yang   Yu, Meijuan Li, Yong Zhang, Yonghai Liu, Lei Shi, Wei Wang,* and Hao Li* Org.   Lett. 2019,   21, 904-907 14 2019-12 Gold(I)-Catalyzed   Glycosylation with Glycosyl Ynenoates as Donors Xiaona   Li, Chenyu Li, Rongkun Liu, Jiazhe Wang, Zixuan Wang, Yan Chen, and You Yang*  Org.   Lett. 2019,   21(23), 9693-9698 15 2019-01 Enantioselective   Construction of CF3-Containing Spirooxindole γ-Lactones via Organocatalytic   Asymmetric Michael/Lactonization Zhong-Tao   YangJianhong Zhao*Wu-Lin YangWei-Ping Deng* Org.   Lett.  2019,   21, 4, 1015-1020 16 2019-06 Enantioselective   Construction of Dihydropyrido[1,2-a]indoles via Organocatalytic   Arylmethylation of 2-Enals with Inert Aryl Methane Nucleophiles Xiang-Feng   Ding, Wu-Lin Yang, Jia Mao, Cong-Xian Cao, and Wei-Ping Deng* Org.   Lett.  2019,   21, 14, 5514-5518 17 2019-03 Selective   visualization of live-cell mitochondrial thiophenols and their induced   oxidative stress process by a rationally designed rhodol-based fluorescent   probe Qimeng   Liu, Anyang Li, Xiaokang Li, Bin Li, Yanhui Zhang, Jian Li, Yuan Guo* Sensor.   Actuator. B-Chem 2019,   283, 820-830 18 2019-03 A   new circular-shape microfluidic network for generating gradients of multiple   substances -design, demonstration and application Yuqing   Chen, Wei Sun, Pei Luo, Min Zhang*, Yuerong Wang, Hongyang Zhang, Ping Hu*. Sensor.   Actuator. B-Chem 2019,   283: 247–254 19 2019-02 Imaging   the Redox States of Live Cells with the Time-Resolved Fluorescence of   Genetically Encoded Biosensors Lei   Li, Changcheng Zhang, Peng Wang, Aoxue Wang, Jiasheng Zhou, Guoqing Chen,   Jianhua Xu, Yi Yang, Yuzheng Zhao*, Sanjun Zhang*, Yang Tian Anal.   Chem.  2019,   91, 3869-3876 20 2019-03 Spiropyran   in situ switching: A real-time fluorescence strategy for tracking DNA   G-quadruplexes in live cells Jin   Li, Xinchi Yin, Bin Li, Xiaokang Li, Yuanjiang Pan, Jian Li, Yuan Guo*. Anal.   Chem.  2019,   91, 5354-5361 21 2019-11 Late-stage   difluoromethylation leading to self-immobilizing fluorogenic probe for the   visualization of enzyme activities in live cells Jialing   Jiang, Qingwei Tan, Shuxuan Zhao, Heng Song, Liqiang Hu and Hexin Xie* Chem. Commun. 2019,   55, 15000 22 2019-07 Highly   Selective and Wash-free Visualization of Resistant Bacteria With a   Relebactam-derived Fluorogenic Probe Yefeng   Chen, Minqiu Xu, Weipan Xu, Heng Song, Liqiang Hu, Shuyuan Xue, Shuangzhan   Zhang, Xiana Qian and Hexin Xie* Chem. Commun. 2019,   55, 9919 23 2019-06 A   naphthalimide-aminal-based pH-sensitive fluorescent donor for   lysosome-targeted formaldehyde release and fluorescence      turn-on readout Hang   Xu,  Shengnan Ma, Qianqian Liu, Lixian   Huang, Peimin Wu, Xiaolin Liu,      Yali Huang, Xiaolei Wang, Huan Xu,* Kaiyan Lou* and Wei Wang* Chem.   Commun. 2019,   55, 7053-7056 24 2019-05 Ligand-controlled   switch in diastereoselectivities: catalytic asymmetric construction of   spirocyclic pyrrolidine-azetidine/oxe(thie)tane derivatives ua   Deng, Renmeng Jia, Wu-Lin Yang, Xingxin Yu* and Wei-Ping Deng*  Chem.   Commun. 2019,   55, 7346-7349 25 2019-04 Tracking   the multiple-step formation of an iron(III) complex and its application in   photodynamic therapy for breast cancer Zhong-Hong   Zhu, Qian Hu, Hui-Ling Pan, Yuexing Zhang, Haibing Xu, Mohamedally Kurmoo, Jin Huang* & Ming-Hua Zeng* Science   China-Chemistry 2019,  62(6), 719-726 26 2019-02 Celastrol   as a tool for the study of the biological events of metabolic diseases Gongcai   Lan, Jie Zhang, Wenbo Ye, Fan Yang, Ang Li, Weiwei He* & Wei-Dong Zhang* Science   China-Chemistry 2019,  62(4), 409-416 27 2019-01 Discovery   of a Natural-Product-Derived Preclinical Candidate for Once-Weekly Treatment   of Type 2 Diabetes Shiliang Li#, Chun Qin#, Shichao Cui#, Hongling Xu, Fangshu Wu, Jiawei Wang, Mingbo Su, Xiaoyu Fang,   Dan Li, Qian Jiao, Ming Zhang, Chunmei Xia, Lili Zhu, Rui Wang, Jia Li,   Hualiang Jiang, Zhenjiang Zhao*, Jing-Ya Li*, Honglin Li* J.   Med. Chem. 2019,   62(5), 2348-2361 28 2019-09 Discovery   of Novel Aryl Carboxamide Derivatives as HypoxiaInducible Factor 1α Signaling   Inhibitors with Potent Activities of Anticancer Metastasis  Mingming   Liu, Yuru Liang, Zhongzhen Zhu, Jin Wang, Xingxing Cheng, Jiayi Cheng,   Binpeng Xu, Rong Li, Xinhua Liu*, Yang Wang* J.   Med. Chem.  2019,   62, 20, 9299-9314 29 2019-10 Nickel(II)-Catalyzed   Diastereo- and Enantioselective Michael/Hemiacetalization Cascade Reaction of   α-Ketoesters with 2-(2-Nitrovinyl)phenols. Chen   Long, Yang Wu-Lin*, Shen Jia-Huan, Deng Wei-Ping.* Adv.   Synth. Catal. 2019,   361(19), 4611-4622. 30 2019-09 Organocatalytic   Asymmetric Inverse-Electron-Demand Diels-Alder Reaction of Pyrrolidone-Dienes   with Enals Wu   Shu-Xiao, Gu Bo-Qi, Xu Hui, Zheng Xing, Luo Xiaoyan*, Deng Wei-Ping.* Adv.   Synth. Catal. 2019,   361(18), 4302-4313. 31 2019-04 The   Employment of Sodium Hydride as a Michael Donor in Palladium-catalyzed   Reductions of a, b-Unsaturated Carbonyl      Compounds Ye   Liu, Yujian Mao, Yanwei Hu, Jingjing Gui, Liang Wang,* Wei Wang, and Shilei   Zhang* Adv.   Synth. Catal. 2019,   361, 1554 - 1558 32 2019-02 Asymmetric   Synthesis of Spirooxindole b-lactams via Isothioureacatalyzed   Mannich/lactamization Reaction of Aryl Acetic Acids with Isatin-derived   Ketimines Jinghai   Jin, Jianhong Zhao,* Wulin Yang, and Weiping Deng*  Adv.   Synth. Catal.  2019,   361, 1592-1596  33 2019-11 Highly   efficient multiple-labeling probes for the visualization of enzyme activities Heng   Song, Yuyao Li, Yefeng Chen, Chenghong Xue, and Hexin Xie* Chem.   Eur. J. 2019,   25, 13994-14002 34 2019-01 Enantioselective   synthesis of 3-amino-hydrobenzofuran-2,5-diones via Cu(i)-catalyzed   intramolecular conjugate addition of imino esters Wu-Lin   Yang,  Zhong-Tao Sun, Jian Zhang, Zhong   Li* and  Wei-Ping Deng Org.   Chem. Front. 2019,6,   579-583  35 2019-05 Transition   metal-free, visible-light-mediated construction of α,β-diamino esters via   decarboxylative radical addition at room temperature Guibing   Wu, Jingwen Wang, Chengyu Liu,   Maolin   Sun, Lei Zhang, Yueyue Ma, Ruihua Cheng and Jinxing Ye* Org.   Chem. Front. 2019,6,   2245-2249  36 2019-06 Self-assembly   of mitochondria-specific peptide amphiphiles amplifying lung cancer cell   death through targeting the VDAC1–hexokinase-II complex Dan Liu,   Angelina Angelova,  Jianwen Liu, Vasil   M. Garamus, Borislav Angelov, Xinlei Zhang, Yawen Li, Guillaume Feger, Na Li*   and Aihua Zou* J.Mater.   Chem. B 2019,   7, 4706 37 2019-01 A novel hydrophilic   polymer-based anion exchanger grafted by quaternized polyethyleneimine for   ion chromatography Zhanqiang Yang,   Zongying Li, Feifang Zhang, Bingcheng Yang*, Shengmao Zhang Talanta 2019,   197, 199-203 38 2019-07 New chalcone   derivatives as potent reversal agents against P-glycoprotein-mediated   multidrug resistance: design, synthesis and biological evaluation Huanhuan   Yin#, Jingjing Dong#, Yingchun Cai#, Ximeng Shi, Hao Wang, Guixia Liu,      Yun Tang*, Jianwen Liu*, Lei Ma* Eur. J. Med. Chem. 2019, 180, 350-366 39 2019-03 Total   Synthesis of the Trisaccharide Antigen of the Campylobacter   jejuni RM1221 Capsular Polysaccharide via de Novo   Synthesis of the 6-Deoxy-d-manno-heptose Building Blocks Xiaoman   Wang, Yan Chen, Junchang Wang, and You Yang* J.   Org. Chem. 2019,   84(5), 2393−2403 40 2019-11 Gold(I)-catalyzed   Intermolecular Rearrangement Reaction of Glycosyl Alkynoic b-Ketoesters for the Synthesis of   4-O-Glycosylated   2-Pyrones Rongkun   Liu, Xiaoqian Li, Xiaona Li, Jiazhe Wang, and You Yang* J.   Org. Chem. 2019,   84(21), 14141-14150 41 2019-07 Synergistic   Catalysis for Asymmetric [3 + 2] Cycloadditions of 2-Indolylmethanols with   α,β-Unsaturated Aldehydes Jia   Mao, Hao Zhang, Xiang-Feng Ding, Xiaoyan Luo,* and Wei-Ping Deng* J.   Org. Chem.  2019,   84, 17, 11186-11194 42 2019-05 Rh(III)-Catalyzed   Hydroarylation of Alkyne MIDA Boronates via C−H Activation of Indole   Derivatives  Xiao   Fei, Chunpu Li, Xinhong Yu*, Hong Liu* J.   Org. Chem.  2019,   84(11),  6840-6850 43 2019-03 admetSAR   2.0: web-service for prediction and optimization of chemical ADMET properties Hongbin   Yang , Chaofeng Lou, Lixia Sun, Jie Li, Yingchun Cai, Zhuang Wang, Weihua Li,   Guixia Liu and Yun Tang* Bioinformatics 2019,   35(6), 1067-1069 44 2019-12 miR-139-5p   reverses stemness maintenance and metastasis of colon cancer stem-like cells   by targeting E2-2 Xiaoying   Ma, Jiajun Liu, Jiyu Li, Yueqi Li,Van Minh Le, Shaoyu Li, Xin   Liang*, Lingshuang Liu*, Jianwen Liu* J. Cell Physiol. 2019,   234(12), 22703-22718 45 2019-08 Vitamin   E succinate-grafted-chitosan/chitosan oligosaccharide mixed micelles loaded   with C-DMSA for Hg2+ detection and detoxification in rat liver Binghui   Wei, Muye He, Xiaoran Cai, Xinyu Hou, Yujie Wang, Jiaojiao Chen, Minbo Lan,   Yanzuo Chen, Kaiyan Lou* and Feng Gao* Int.   J. Nanomed. 2019,   14, 6917-6932 46 2019-07 Construction   of Escherichia coli cell factories for crocin biosynthesis  Wen   Wang, Ping He, Dongdong Zhao, Lijun Ye, Longhai Dai, Xueli Zhang, Yuanxia   Sun*, Jing Zheng* and Changhao Bi*  Microb.   Cell Fact.           2019,   18, 120 47 2019-03 Combined   Cancer Chemo-Photodynamic and Photothermal Therapy Based on   ICG/PDA/TPZ-Loaded Nanoparticles Xiaqin   Huang, Junru Wu, Muye He, Xinyu Hou, Yan Wang, Xiaoran Cai,‡Hongliang Xin,   Feng Gao,* and Yanzuo Chen* Mol.   Pharmaceutics 2019，16,   2172- 2183. 48 2019-10 EpCAM   Aptamer-Functionalized Cationic Liposome-Based Nanoparticles Loaded with   miR-139-5p for Targeted Therapy in Colorectal Cancer.  Yuyu   Zhao, Jiajun Xu, Van Minh Le, Qianyi Gong, Shaoyu Li, Feng Gao, Lei Ni*,   Jianwen Liu*, Xin Liang*.  Mol.   Pharmaceutics  2019,   16(11), 4696-4710 49 2019-01 Efficient   ovalbumin delivery using a novel multifunctional micellar platform for   targeted melanoma immunotherapy Muye   Heb, Lei Huangb, Xinyu Houb, Chen Zhongb, Zaina Ait Bachirb, Minbo   Lana,      Rongjun Chenc*, Feng Gao* Int.   J. Pharmaceut. 2019,   560, 1-10 50 2019-02 Fabrication   of a two-membrane configured electrodialytic methanesulfonic acid generator   for ion chromatography Yifei   Lu, Lili Zhao, Shiyuan Lin, Feifang Zhang and Bingcheng Yang*   Analyst 2019,   144, 2411 51 2019-06 Microfluidic   co-culture of liver tumor spheroids with stellate cells for the investigation   of drug resistance and intercellular interactions Yuqing   Chen, Wei Sun, Lu Kang, Yuerong Wang, Min Zhang, Hongyang Zhang and Ping Hu* Analyst 2019,   144, 4233-4240 52 2019-03 A   ratiometric near-infrared fluorescence strategy based on spiropyran in situ   switching for tracking dynamic changes of live-cell lysosomal pH. Jin   Li#, Xiaokang Li#, Jianbo Jia#, Xi Chen, Yinjuan Lv, Yuan Guo*, Jian Li*. Dyes   Pigments 2019,   166, 433-442 53 2019-01 Cyclodextrin/chitosan   nanoparticles for oral ovalbumin delivery: Preparation, characterization and   intestinal mucosal immunity in mice Muye   He, Chen Zhong, Huibing Hu, Yu Jin, Yanzuo Chen, Kaiyan Lou, Feng Gao* Asian   J. Pharm. Sci. 2019,14(2):193-203 54 2019-04 Nitazoxanide,   an anti-parasitic drug, efficiently ameliorates learning and memory   impairments in AD model mice Lei   Fan#, Xiao-xia Qiu#, Zhi-yuan Zhu, Jian-lu Lv, Jian Lu, Fei Mao, Jin Zhu,   Jia-ying Wang, Xiao-wei Guan, Jing Chen, Jin Ren, Ji-ming Ye, Yong-hua Zhao,   Jian Li*, Xu Shen* Acta   Pharmacol. Sin. 2019,   40, 1279-1291 55 2019-02 C11,   a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, suppresses   breast cancer metastasis and angiogenesis Zhuo   Chen, Linjiang Tong, Baiyou Tang, Hongyan Liu, Xin Wang, Tao Zhang, Xianwen   Cao, Yi Chen, Honglin Li, Xuhong Qian, Yufang Xu*, Hua Xie*, Jian Ding*. Acta   Pharmacol. Sin. 2019,   40(6), 823-832 56 2019-03 In   silico prediction of endocrine disrupting chemicals using single-label and   multi-label models Lixia   Sun, Hongbin Yang, Yingchun Cai, Weihua Li, Guixia Liu, and Yun Tang* J.   Chem. Inf. Model. 2019,   59(3), 973-982 57 2019-03 Computational   prediction of site of metabolism for UGT-catalyzed reactions Yingchun   Cai, Hongbin Yang, Weihua Li, Guixia Liu, Philip W. Lee, and Yun Tang* J.   Chem. Inf. Model. 2019,   59(3), 1085-1095 58 2019-01 Stearic   Acid-Grafted Chitooligosaccharide Nanomicelle System with Biocleavable   Gadolinium Chelates as a Multifunctional Agent for Tumor Imaging and Drug   Delivery Chuhua   Xin, Xiuzhong Yao, Bin Du, Weiyu Yang, Liuguo Wang, Lirong Ma, Weiyu Weng* Pharmaceutical   Research 2019,   36:10 59 2019-03 Rational   design of novel selective dual-target inhibitors of acetylcholinesterase and   monoamine oxidase B as potential anti-Alzheimer's disease agents Yixiang   Xu#, Jian Zhang#, Huan Wang#, Fei Mao, Keting Bao, Wenwen Liu, Jin Zhu,   Xiaokang Li*, Haiyan Zhang*, Jian Li* ACS   Chem. Neurosci.  2019,   10, 482-496 60 2019-04 A   poly(glycidylmethacrylate-divinylbenzene)-based anion exchangerfor ion   chromatography Zhanqiang Zhanqiang Yang, Min Gao,   Zongying Li, Feifang Zhang, Shengmao Zhang, Bingcheng Yang* J. Chromatogr. A 2019,   1596, 79-83 61 2019-06 A   bipolar membrane-based cation electrolytic membrane suppressor for ion   chromatography Lili Zhao,   Yifei Lu, Feifang Zhang, Bingcheng Yang* J.   Chromatogr. A 2019,   1603,422-425 62 2019-05 Discovery   of potent and non-covalent reversible EGFR kinase inhibitors of EGFR   L858R/T790M/C797S Qiannan   Li#, Tao Zhang#, Shiliang Li#, Linjiang Tong, Junyu Li, Zhicheng Su, Fang Feng, Deheng Sun,   Yi Tong, XiaWang, Zhenjiang Zhao, Lili Zhu, Jian Ding, Honglin Li*, Hua Xie*,   Yufang Xu* ACS   Med. Chem. Lett. 2019,   10(6), 869-873 63 2019-03 Structural   insights into a novel Ca2+-independent PL6 alginate lyase from Vibrio OU02   identify the possible subsites responsible for product distribution Qianqian   Lyu, Keke Zhang, Yanhong Shi, Weihua Li, Xiaotong Diao, and Weizhi Liu* BBA-Gen.   Subj.  2019,   1863, 1167-1176 64 2019-03 Absorption   Characteristics of Chitobiose and Chitopentaose in the Human Intestinal Cell   Line Caco‑2 and Everted Gut Sacs  Ping   Chen, Mengyao Zhao, Qiming Chen, Liqiang Fan, Feng Gao, and Liming Zhao*  J.   Agric. Food Chem.  2019,   67, 4513-4523 65 2019-04 Investigating   molecular interactions of high-loaded glipizide-HPMCAS microparticles by   integrated experimental and modeling techniques Qiang   Li, Qianqian Zhao, Qiufang Jing, Xiaosi Ma, Ning Chen, Guobin Ren, Defang   Ouyang*, Fuzheng Ren* Eur.   J. Pharm. Sci. 2019,   131, 127-135 66 2019-05 Insights   into mechanisms and severity of drug-induced liver injury via computational   systems toxicology approach Yayuan   Peng, Zengrui Wu*, Hongbin Yang, Yingchun Cai, Guixia Liu, Weihua Li, Yun   Tang* Toxicol. Lett. 2019, 312, 22-33 67 2019-10 Prediction   of the allergic mechanism of haptens via a   reaction-substructure-compound-target-pathway network system Peiwen   Di, Zengrui Wu, Hongbin Yang, Weihua Li, Yun Tang*, Guixia Liu* Toxicol. Lett. 2019, 317, 68-81 68 2019-02 Synthesis   of the beta-Linked GalNAc-Kdo Disaccharide Antigen of the Capsular   Polysaccharide of Kingella kingae KK01 Liqin   Zhuang, Yan Chen, Qixin Lou and You Yang*  Org.   Biomol. Chem. 2019,   17(7), 1694-1697 69 2019-07 Highly   Convergent Synthesis of a b-Mannuronic   Acid Alginate Hexadecasaccharide Dingyi   Pan, Liangliang Zhang, Qingting Hua and You Yang* Org.   Biomol. Chem. 2019,   17(7), 6174-6177 70 2019-07 Gold(I)-promoted   a-Selective Sialylation of   Glycosyl ortho-Hexynylbenzoates   for the Latent-active Synthesis of Oligosialic Acids Jiazhe   Wang, Qixin Lou, Jingjing Rong and You Yang* Org.   Biomol. Chem. 2019,   17(27), 6580-6584.  71 2019-10 Primary   amine catalyzed diastereo- and enantioselective Michael reaction of   thiazolones and α,β-unsaturated ketones Min   Lu, Hong Li, Chuncheng Zou, Jianchang Li, Chengyu Liu, Maolin Sun, Yueyue Ma,   Ruihua Cheng and Jinxing Ye* Org.   Biomol. Chem.  2019,   17, 9305-9312 72 2019-10 Biological   and anti-vascular activity evaluation of ethoxy-erianin phosphate as a   vascular disrupting agent Wenshuang   Yuan, Chang Su, Xiaotong Yang, Yueqi Li, Yiou Cao*, Xin   Liang*, Jianwen Liu* J. Cell Biochem. 2019,   120(10), 16978-16989 73 2019-01 17-allylamino-17-demethoxygeldanamycin   impeded chemotherapy through antioxidant activation via reducing reactive   oxygen species-induced cell death Yueqi   Li, Yiyang Chen, Cen Qiu, Xiaoying Ma, Kecheng Lei, Guoxiang Cai*, Xin Liang*, Jianwen Liu*. J. Cell Biochem. 2019,   120, 1560-1576 74 2019-02 Modified   rivaroxaban microparticles for solid state properties improvement based on   drug-protein/polymer supramolecular interactions Ning   Chen, Peiwen Di, Shangqi Ning, Wenjun Jiang, Qiang Li, Qiufang Jing, Guobin   Ren, Yan Liu, Yun Tang, Guixia Liu*, Fuzheng Ren* Powder Technol. 2019,   344, 819-829 75 2019-04 Small   nucleolar RNA host gene 1 promotes development and progression of colorectal   cancer through negative regulation of miR‐137 Yang   Fu*, Yuhan Yin, Sanfei Peng, Ge Yang, Yang Yu, Changqing Guo, Yanru Qin,   Xiefu Zhang, Wen Xu, Yiyu Qin* Mol.   Carcinogen.  2019,   58, 2104-2117 76 2019-01 Exploring   the effect of PVP on the spherical agglomeration process and micromeritic   properties of ascorbic acid Saixu   Huang, Yan Liu, Yaru Zhou, Qiang Li, Guobin Ren, Qiufang Jing, Fuzheng Ren* Powder Technol. 2019,   342, 929-937 77 2019-01 Novel   dual inhibitors against FP-2 and PfDHFR as potential antimalarial agents:   Design, synthesis and biological evaluation Wenhua   Chen#, Xue Yao#, Zhenghui Huang#, Fei Mao, Longfei Guan, Yun Tang, Hualiang   Jiang, Jian Li, Jin Huang*, Lubin Jiang*, Jin Zhu* Chin.   Chem. Lett.  2019,   30, 250-254 78 2019-01 NanoparticlestructuretransformationofmPEGgraftedchitosanwith      rigid backboneinducedby a-cyclodextrin Lei   Huang, JiaojiaoChen, MuyeHe, XinyuHou, YibenLu, KaiyanLou, FengGao* Chin.   Chem. Lett.  2019,   30, 163-166 79 2019-10 Crystal   structure and physical stability of ginsenoside compound-K solvates Jinyao   Chen, Wenming Zhu, Weijie Ji, Bin Zhu, Chunyang Guo, Minghui Qi* and Guobin   Ren* CrystEngComm 2019,   21, 7313-7321 80 2019-07 Economical   Process for Preparation of the 19-nor A Ring of Paricalcitol from   (−)-Shikimic Acid Shengfeng   Zhou, Runyu Zhu, Jingwen Hu, Lixiong Zhang, Qian Lu, and Xinhong Yu* Org.   Process Res. Dev.  2019,   23, 9, 1887-1891 81 2019-03 eSHAFTS:   Integrated and graphical drug design software based on 3D molecular   similarity Gaoqi   He, Yiping Song, Wenhao Wei, Xia Wang, Xingjian Lu*, Honglin Li* J.   Comput. Chem. 2019,   40, 826-838 82 2019-07 A   novel derivative of Artemisinin inhibits cell proliferation and metastasis   via down-regulation of Cathepsin K in breast cancer Xiangyu   Gu, Yayuan Peng, Yuyu Zhao, Xin Liang∗, Yun Tang∗, Jianwen Liu* Eur. J. Pharmacol. 2019, 858, 172382 83 2019-05 In   silico prediction of chemical reproductive toxicity using machine learning Changsheng   Jiang, Hongbin Yang, Peiwen Di, Weihua Li, Yun Tang*, Guixia Liu* J. Appl.   Toxicol.  2019, 39, 844-854 84 2019-05 Prediction   of the skin sensitizing potential and potency of compounds via   mechanism-based binary and ternary classification models Peiwen   Di, Yongmin Yin, Changsheng Jiang, Yingchun Cai, Weihua Li, Yun Tang⁎, Guixia   Liu* Toxicol. in Vitro 2019, 59, 204-214 85 2019-07 Structural   Optimization and Structure-Activity Relationship of 4-Thiazolidinone   Derivatives as Novel Inhibitors of Human Dihydroorotate Dehydrogenase. Fanxun   Zeng, Lina Quan, Guantian Yang, Tiantian Qi, Letian Zhang, Shiliang Li, Honglin Li, Lili Zhu*, Xiaoyong Xu* Molecules 2019,   24(15), 2780 86 2019-06 Separating   graphene quantum dots by lateral size through gel column chromatography Wentian   Wu, Jiamin Cao, Min Zhong, Haixia Wu, Fangwei Zhang, Jingyan Zhang and Shouwu   Guo* RSC   Adv. 2019,9,   18898 87 2019-11 3(2H)-pyridazinone   derivatives: a new scaffold for novel plant activators Qinjie   Shi, Yanxia Shi, Kang Chang, Jianqin Chen, Zhenjiang Zhao, Weiping Zhu,   Yufang Xu*, BaoJu Li* and Xuhong Qian* RSC   Adv. 2019,   9, 36204 88 2019-01 Phenylboronic   acid derivative-modified (6,5) single-wall carbon nanotube probes for   detecting glucose and hydrogen peroxide Yunfan   Qiao, Rushi Zhao, Min Zhang,* Hongyang Zhang, Yuerong Wang and Ping Hu* RSC   Adv. 2019,   9, 225 89 2019-01 Hypercrosslinked   strong anion-exchange polymers for selective extraction of fluoroquinolones   in milk samples Xiaoping   Liang, Ping Hu, Hongyang Zhang*, WenTan* J.   Pharmaceut. Biomed. Analysis      2019, 166, 379–386 90 2019-12 Probing   the degradation mechanism of forsythiaside A and simultaneous determination   of three forsythiasides in Forsythia preparations by a single marker Minghui   Qi,Shiyi Zhao,Bin Zhou, Min Zhang*, Hongyang Zhang,Yuerong Wang, Ping Hu* J.   Sep. Sci.  2019,   42, 3503–3511 91 2019-05 Novel   Piperazino-Enaminones Decrease Pro-inflammatory Cytokines Following   Hemarthrosis in a Hemophilia Mouse Model Chen Zhong, Doreen Szollosi*,   Junjiang Sun*, Baolai Hua, Ola Ghoneim, Ashley Bill, Yingping Zhuang &   Ivan Edafiogho  Inflammation  2019,   42, 1719–1729 92 2019-01 Inhibitory   mechanism of a substrate-type angiotensin I-converting enzyme inhibitory   peptide Junjie   Wu, Dewei Xie, Xujun Chen, Ya-Jie Tang, Lixin Wang, Jingli Xie*, Dongzhi Wei* Process   Biochem. 2019,   79, 97-104 93 2019-06 Discovery   and Biological Evaluation of Pyrimido[4,5-d]pyrimidine-2,4(1H,3H)-dione   Derivatives as Potent Bruton's Tyrosine Kinase Inhibitors Yanyan   Diao, Xiaoyu Fang, Peiran Song, Mengzhen Lai, Linjiang Tong, Yongjia Hao, Dou   Dou, Yingqiang Liu, Jian Ding, Zhenjiang Zhao*, Hua Xie*, Honglin   Li* Bioorg.   Med. Chem. 2019,   27(15) , 3390-3395 94 2019-09 CH(II),   a cerebroprotein hydrolysate, exhibits potential neuro-protective effect on   Alzheimer’s disease Zehui   Liu, Wanyan Wang, Tingyu Huang, Cunfang Wang, Ying Huang*,Yong Tang*, Jin Huang* PLoS   One 2019,   14(9), e0222757 95 2019-02 A   carbapenem-based off-on fluorescent probe for specific detection of   metallo-b-lactamase activities Wuyu   Mao, Yaqun Wang, Xiana Qian, Lingying Xia, and Hexin Xie* ChemBioChem  2019,   20, 511-515 96 2019-09 In   Vitro and In Vivo Study on the Effect of Lysosome-associated Protein   Transmembrane 4 Beta on the Progression of Breast Cancer  Deyou   Tao,* Junqing Liang,* Yihong Pan, Yanting Zhou, Ying Feng, Lin Zhang,   Jingjing Xu, Hui Wang, Ping He, Jie Yao, Yang Zhao, Qinjie Ning, Wen Wang,   Wei Jiang, Jing Zheng, and Xia Wu* J.   Breast Cancer  2019, 22(3), 375-386 97 2019-05 Simultaneous   quantification of urinary purines and creatinine by ultra high performance   liquid chromatography with ultraviolet spectroscopy and quadrupole time‐of‐flight mass spectrometry: Method development, validation, and   application to gout study YuanYuan,   MinJiang, Hongyang Zhang*, Ju Liu, Min Zhang, Ping Hu* J.   Sep. Sci.  2019,   42, 2523–2533 98 2019-04 Design,   synthesis and structure-activity relationship study of aminopyridine   derivatives as novel inhibitors of Janus Kinase 2. Wanqi   Wang, Yanyan Diao, Wenjie Li, Yating Luo, Tingyuan Yang, Yuyu Zhao, Tiantian   Qi, Fangling Xu, Xiangyu Ma, Huan Ge, Yingfan Liang, Zhenjiang Zhao, Xin   Liang, Rui Wang, Lili Zhu*, Honglin Li*, Yufang Xu* Bioorg.   Med. Chem. Lett. 2019,   29, 1507-1513 99 2019-10 Synthesis   and biological evaluation of 3-carbamate smilagenin derivatives as potential   neuroprotective agents.  Cong   Zhang, Yan Wu, Jie Li, Guixiang Yang, Lin Su, Yan Huang, Rui Wang*, Lei   Ma*  Bioorg.   Med. Chem. Lett.  2019, 29, 126622 100 2019-01 A   carbapenem-based fluorescence assay for the screening of metallo-b-lactamase   inhibitors Xiana   Qian, Shuangzhan Zhang, Shuyuan Xue, Wuyu Mao, Minqiu Xu, Weipan Xu, Hexin   Xie* Bioorg.   Med. Chem. Lett.  2019,   29(2), 322-325 101 2019-01 GM1   Ameliorates Lead-Induced Cognitive Deficits and Brain Damage Through   Activating the SIRT1/CREB/BDNF Pathway in the Developing Male Rat Hippocampus Fei Chen, Can-Can Zhou, Yin Yang,   Jian-Wen Liu & Chong-Huai Yan* Biol.   Trace Elem. Res.  2019,   190, 425–436 102 2019-01 ADMET-score   – a comprehensive scoring function for evaluation of chemical ADMET   properties Longfei   Guan, Hongbin Yang, Yingchun Cai, Lixia Sun, Peiwen Di, Weihua Li,      Guixia Liu and Yun Tang* MedChemComm 2019,   10(1), 148-157 103 2019-06 A   4-OTBS Benzyl-based Protective Group for Carboxylic Acids Zhijun   Fang, Yuyao Li, Hexin Xie* Tetrahedron   Lett.   2019,   60, 1658-1662 104 2019-05 Synthesis   of 3-aminoindan-1-one derivatives from 2-acetylbenzaldehydes and secondary   amines by Mannich annulation Yong   Zhang, Yonghai Liu, Shuai Zhang, Lei Shi, Wei Wang* and Hao Li* Tetrahedron   Lett.   2019,   60, 1463-1466 105 2019-05 Computational   insights into the different catalytic activities of CYP3A4 and CYP3A5 toward   schisantherin E. Yuhan   Xue, Junhao Li, Zengrui Wu, Guixia Liu, Yun Tang, and Weihua Li* Chem.   Biol. Drug Des.  2019,   93, 854-864 106 2019-07 Computational   insights into the interaction mechanisms of ERR with endogenous ligand   cholesterol Dongping   Li, Yingchun Cai, Dan Teng, Weihua Li, Yun Tang*, Guixia Liu* Chem.   Biol. Drug Des.  2019, 94, 1316-1329 107 2019-04 Timely   and large dose of clotting factor IX provides better joint wound healing   after hemarthrosis in hemophilia B mice Ping   He, Feixu Zhang, Chen Zhong, Min Li, Jing Zheng, Baolai Hu* & Junjiang Sun* Int.   J. Hematol. 2019,   110, 59–68 108 2019-03 Drug   design of undruggable targets   Jie Wang, Shiliang Li, Honglin Li* Chin.   J. Chem. 2019,   37, 501-512 109 2019-10 Design   and Synthesis of a Series of Novel Macrocycle Janus Kinase 2 Inhibitors Yanling   Wang, Huan Ge, Disha Wang, Huan He, Lu Li, Yanyan Diao, Zihao Shen, Lili Zhu,   Shiliang Li, Zhenjiang Zhao,* and Honglin Li* Chin.   J. Chem.  2019,   37, 1259-1263 110 2019-01 Nickel(II)-Catalyzed   Diastereo- and Enantioselective [3+2] Cycloaddition of α-Ketoesters with   2-Nitrovinylindoles and 2-Nitrovinylpyrroles Wu-Lin   Yang, Zhong-Tao Sun, Hao Sun, and Wei-Ping Deng*  Chin.   J. Chem.  2019,   37, 216-220 111 2019-09 Structure   properties of scoparone: Polymorphs and cocrystals Jin-yao   Chen, Xiao-yu Wang, Ming-huang Hong, Dong-xu Yi, Ming-hui Qi*, Guo-bin Ren* J.   Mol. Struct. 1191:   323-336 112 2019-10  VB1 Promoted Green Synthesis of Chalcones   and its Neuroprotection Potency Evaluation. Huanhuan   Yin, Ximeng Shi, Hao Wang, Guixia Liu, Lei Ma*. Processes 2019,   7, 236 113 2019-08 Gold(I)-promoted   Synthesis of a b-(1,3)-Glucan   Hexadecasaccharide via the Highly Convergent Strategy Zixuan   Wang, Qingting Hua, You Yang* Carbohydr.   Res. 2019,   482, 107735 114 2019-07 Design,   synthesis and biological evaluation of novel indone derivatives as selective   ERβ modulators Xi-Xi   Liu, Mei-Lin Tang, Chen Zhong, Yun Tang, Jian-Ming Yu, Xun Sun* Med.   Chem. Res. 2019,   28(7), 1010-1026 115  2019-04 Synthesis   and Structure Activity Relationships of Novel Dehydroepiandrosterone   Derivatives as Potent Neuroprotective Agents and Nitric Oxide Production   Inhibitors.  Haixian   Gan, Yuhang Wu, Kexin Jiang, Songlan Ge, Yuqian Yao,   Rui Wang*, Lei Ma* ChemistrySelect 2019,   4, 11678-11682. 116 2019-05 In   silico prediction of chemical aquatic toxicity for marine crustaceans via   machine learning methods Lin   Liu, Hongbin Yang, Yingchun Cai, Qianqian Cao, Lixia Sun, Zhuang Wang, Weihua   Li, Guixia Liu, Philip W. Lee and Yun Tang* Toxicol. Res. 2019, 8(3), 341-352 117 2019-02 Identification   of novel PI3Kδ inhibitors by docking, ADMET prediction and molecular dynamics   simulations Ya-Ya   Liu, Xiao-YanFeng, Wen-Qing Jia, Zhi Jing, Wei-Ren Xu, Xian-Chao Cheng* Comput.   Biol. Chem.  2019, 78, 190-204 118 2019-02 Identification   of novel PPARα/γ dual agonists by pharmacophore screening, docking analysis,   ADMET prediction and molecular dynamics simulations Xiao-Yan   Feng, Wen-Qing Jia, Xin Liu, Zhi Jing, Ya-Ya Liu, Wei-Ren Xu, Xian-Chao   Cheng* Comput.   Biol. Chem. 2019,   78, 178-189 119  2019-04  Isolation of new glycosides from Anemarrhena   asphodeloides rhizome and screening of their anticancer activity.  Pham   Van Khang, Nguyen Thi Hien Lan, Le Quang Truong, Mai Thi Minh Chau, Mai Xuan   Truong, Dinh Thuy Van, Nguyen Thi Quynh Anh, Lei Ma*. Lett.   Org.Chem. 2019,   16, 474-477 120 2019-06 Lactose   induced redox-dependent senescence and activated Nrf2 pathway. Shuli   Xing, Lanxin Zhang, Huiling Lin, Zhifan Mao, Keting Bao, Peng Hao, Zhe Pei,   Jian Li*, Zelan Hu* Int.   J. Clin. Exp. Pathol.  2019,   12, 2034-2045 121 2019-05 Neuroprotective   effects of sarsasapogenin-AA13 via autophagy and MAPK pathway Ling   Yu , Cui Huang  , Dong Dong, Yan Huang,   Lei Ma*, Rui Wang* Int.   J. Clin. Exp. Med. 2019,   12(5), 4920-4927 122 2019-12  Practical synthesis of C1 deuterated   aldehydes enabled by NHC catalysis Huihui   Geng, Xiaobei Chen*, Jingjing Gui, Yueteng Zhang , Zuyuan Shen, Pengfei Qian,   Junwei Chen1, Shilei Zhang* and Wei Wang* Nat.   Catal. 2019,   2, 1071-1077 123 2019-03 Pharmacodynamics   simulation of HOEC by a computational model of arachidonic acid metabolic   network Wen   Yang, Xia Wang, Kenan Li, Yuanru Liu, Ying Liu*, Rui Wang*, Honglin Li* Quant.   Biol.  2019, 7(1), 30-41 124 2019-04 Insights   into the antineoplastic mechanism of Chelidonium majus via systems   pharmacology approach Xinzhe   Xiao, Zehui Chen, Zengrui Wu, Tianduanyi Wang, Weihua Li, Guixia Liu, Bo   Zhang,*, and Yun Tang* Quant.   Biol. 2019, 7(1), 42-53 125 2019-08  ( 6，5) 手性单壁碳纳米管近红外荧光探针检测多巴胺. 赵如诗，李洁，乔云帆，胡坪，章弘扬，王月荣，张敏* 分析试验室  2019，38（8）：897 -901 126 2019-02 (6,5)手性单壁碳纳米管的双水相分离及其对紫杉醇的载药研究.  李洁，张敏*，章弘扬，王月荣，胡坪. 华东理工大学学报（自然科学版） 2019，45（1）：67-73 127 2019-05 灵芝子实体中三萜类物质抗肿瘤活性的谱效关系 郑洁、唐庆九、张劲松、王金艳、唐传红、冯娜、韩伟* 菌物学报 2019,   38(07), 1165-1172 128 2019-06 灵芝子实体中不同极性的三萜体外抗肿瘤及抗炎活性比较 郝萌萌、王金艳、冯娜、张劲松、唐庆九、韩伟* 菌物学报 2019,   38(06), 917-925 129 2019-09 HPLC法测定灵芝孢子粉中三萜含量 杨志空、韩伟、冯娜、张劲松、王晨光、周靖、王金艳、唐庆九 菌物学报 2019,   38(9), 1-9 130 2019-09 蝉棒束孢菌子实体对大鼠肾小管上皮细胞的影响 覃丽霞，尹彬，任盼，王静春，王玉芹*，王春丽* 菌物学报、科学出版社 2019,   38(9), 1501-1509 131 2019-03 超声波辅助提取川芎中欧当归内酯A的动力学模型 赵少甫、彭茹洁、邓祥、郑洁、韩伟* 南京工业大学学报(自然科学版) 2019,   41(02), 224-231 132 2019-01 Plackett-Burman试验联用满意度函数-响应面法优化白及多糖絮凝纯化工艺 彭茹洁、赵少甫、王承潇、韩伟* 南京工业大学学报(自然科学版) 2019,   41(01), 57-63 133 2019-09 蛹虫草多糖提取分离方法的研究进展 李小一、刘美岐、窦启航、刘雅琦、韩伟* 山东化工 2019,   48(18), 53-54, 56 134 2019-09 酶法、β-环糊精协同超声提取茶多酚及抗氧化活性 韩伟、邓祥 徐州工程学院学报(自然科学版) 2019,   34(03), 34-42