2012年

序号 论文名称 作者 刊物、出版社名称 卷、期（或章节）、页 SCI影响因子 1 An   organocatalytic cascade approach toward polysubstituted quinolines and chiral   1,4-dihydroquinolines-unanticipated effect of N-protecting groups Xinshuai   Zhang, Xixi Song, Hao Li, Shilei Zhang, Xiaobei Chen, Xinhong Yu*, and Wei   Wang* Angew. Chem. Int.   Ed.  2012,51(29),7282-7286 13.455 2 Stabilization   and Induction of Oligonucleotide i‑Motif Structure via Graphene Quantum Dots Xin   Chen, Xuejiao Zhou, Ting Han,  JiayingWu, Jingyan Zhang*, and Shouwu Guo* ACS NANO. 2012,DOI:   10.1021/nn304673a 10.774 3 A   three-channel fluorescent probe that distinguishes peroxynitrite from   hypochlorite Quanjuan   Zhang, Zhichuan Zhu, Yongli Zheng, Jiagao Cheng, Na Zhang, Yitao Long, Jing   Zheng*, Xuhong Qian*, and Youjun Yang* J. Am. Chem. Soc. 2012,134(45),18479-18482 9.907 4 Pseudolarenone,   an unusual nortriterpenoid lactone with a fused 5/11/5/6/5 ring system   featuring an unprecedented bicyclo[8.2.1]tridecane core from Pseudolarix   amabilis Bo   Li, Deyun Kong, Yunheng Shen, Kali Fu, Rongcai Yue, Zhuzhen Han, Hu Yuan,   Qingxin Liu, Lei Shan, Huiliang Li, Xianwen Yang, and Weidong Zhang* Chem. Commun. 2012,DOI:10.1039/c2cc37742j 6.169 5 Direct   transformation of simple enals to 3,4-disubstituted benzaldehydes under mild   reaction conditions via an organocatalytic regio- and chemoselective   dimerization cascade Xixi Song, Xinshuai Zhang, Shilei Zhang, Hao Li*, and Wei Wang* Chem. Eur. J. 2012,18(32),9770-9774 5.925 6 Pseudolaridimers   A and B,Hetero-Cycloartane Labdane Diels                                                                                                   Alder Adducts from the Cone of Pseudolarix amabilis Bo   Li, Deyun Kong, Yunheng Shen, Hu Yuan, Rongcai Yue, Yiren He, Lu Lu, Lei   Shan,Huiliang Li, Ji Ye, Xianwen Yang, Juan Su,  Runhui Liu, and Weidong Zhang* Org. Lett. 2012,14(21),5432-5435 5.862 7 PTID:   an integrated web resource and computational tool for agrochemical discovery Jiayu   Gong, Xiaofeng Liu, Xianwen Cao, Yanyan Diao, Daqi Gao, Honglin Li*, and   Xuhong Qian* Bioinformatics  2012,doi:10.1186/1471-2105-9-104 5.468 8 Discovery   and optimization of 1,3,4-trisubstituted-pyrazolone derivatives as novel,   potent, and nonsteroidal farnesoid X receptor (FXR) selective antagonists Huang   Huang, Ying Yu, Zhenting Gao, Yong Zhang, Chenjing Li, Xing Xu, Hui Jin,   Wenzhong Yan, Ruoqun Ma, Jin Zhu, Xu Shen, Hualiang Jiang, Lili Chen*, and   Jian Li* J. Med. Chem. 2012,55(16),7037-7053 5.248 9 Discovery   of diverse human dihydroorotate dehydrogenase inhibitors as immunosuppressive   agents by structure-based virtual screening Yanyan   Diao, Weiqiang Lu, Huangtao Jin, Junsheng Zhu, Le Han, Minghao Xu, Rui Gao,   Xu Shen, Zhenjiang Zhao, Xiaofeng Liu, Yufang Xu, Jin Huang*, and Honglin Li* J. Med. Chem. 2012,55(19),9341-8349 5.248 10 Discovery   of Inhibitors To Block Interactions of HIV‑1 Integrase with Human LEDGF/p75   via Structure-Based Virtual Screening and Bioassays Guoping   Hu, Xi Li, Xuan Zhang, Yaozong Li, Lei Ma, Liumeng Yang, Guixia Liu, Weihua   Li, Jin Huang*, Xu Shen, Lihong Hu*, Yongtang Zheng*, and Yun Tang* J. Med. Chem. 2012,   55(22),10108-10117 5.248 11 Discovery   of novel small molecule inhibitors of dengue viral NS2B-NS3 protease using   virtual screening and scaffold hopping Jing   Deng, Ning Li, Hongchuan Liu, Zhili Zuo, Oi Wah Liew, Weijun Xu, Gang Chen,   Xiankun Tong, Wei Tang, Jin Zhu, Jianping Zuo, Hualiang Jiang, Caiguang   Yang*, Jian Li*, and Weiliang Zhu* J. Med. Chem. 2012,55(14),6278-6293 5.248 12 Prediction   of Drug-Target Interactions and Drug Repositioning via Network-Based   Inference Feixiong   Cheng, Chuang Liu,  Jing Jiang,   Weiqiang Lu, Weihua Li, Guixia Liu, Weixing Zhou*, Jin Huang*, Yun Tang* PLoS Comput. Biol. 2012,8(5),doi:10.1371/journal.pcbi.1002503 5.215 13 MiR-297   modulate multidrug resistance in human colorectal carcinoma by   down-regulating MRP-2. Ke   Xu, Xin Liang, Ke Shen, Daling Cui, Yuanhong Zheng,Jianhua Xu, Zhongze Fan,   Yanyan Qiu, Qi Li, Lei Ni, and Jianwen Liu* Biochem. J. 2012,84,, 320–330 4.897 14 Nuclease   Activity and Cytotoxicity Enhancement of the DNA Intercalators via Graphene   Oxide Bin   Zheng, Chong Wang, Congyu Wu, Xuejiao Zhou, Min Lin, Xiaochen Wu, Xiaozhen   Xin, Xin Chen, Lin Xu, Hui Liu, Jing Zheng, Jingyan Zhang*, and Shouwu Guo* J. Phys. Chem. C 2012,116(29),15839-15846 4.805 15 MiR-139   inhibits invasion and metastasis of colorectal cancer by targeting the type I   insulin-like growth factor receptor Ke   Shen, Qiannan Liang, Ke Xu, Daling Cui , Lin Jiang, Peihao Yin, Yanhua Lu, Qi   Li*, and Jianwen Liu* Biochem. Pharmacol. 2012,84(3),320-330 4.705 16 admetSAR:   A Comprehensive Source and Free Tool for Assessment of Chemical ADMET   Properties Feixiong   Cheng, Weihua Li, Yadi Zhou, Jie Shen, Zengrui Wu, Guixia Liu, Philip W. Lee,   and Yun Tang* J. Chem. Inf. Model. 2012,52(12),3099-3105 4.675 17 In   Silico Assessment of Chemical Biodegradability Feixiong   Cheng, Yutaka Ikenaga, Yadi Zhou, Yue Yu, Weihua Li, Jie Shen, Zheng Du, Lei   Chen, Congying Xu, Guixia Liu, Philip W. Lee, and Yun Tang*       J. Chem. Inf. Model. 2012, 52, 655-669 4.675 18 In   silico Prediction of Chemical Ames Mutagenicity Congying   Xu, Feixiong Cheng, Lei Chen, Zheng Du, Weihua Li, Guixia Liu*, Philip W.   Lee, and Yun Tang* J. Chem. Inf. Model. 2012, 52, 2840-2847 4.675 19 Performance   Evaluation of 2D Fingerprint and 3D Shape Similarity Guoping   Hu, Guanglin Kuang, Wen Xiao, Weihua Li, Guixia Liu, and Yun Tang* J. Chem. Inf. Model. 2012, 52, 1103-1113 4.675 20 Unbinding   Pathways of GW4064 from Human Farnesoid X Receptor As Revealed by Molecular   Dynamics Simulations Weihua   Li, Jing Fu, Feixiong Cheng, Mingyue Zheng* , Jian Zhang, Guixia Liu, and Yun   Tang* J. Chem. Inf. Model. 2012, 52, 3043-3052 4.675 21 Investigation   of Indazole Unbinding Pathways in CYP2E1 by Molecular Dynamics Simulations Zhonghua   Shen, Feixiong Cheng, You Xu,Jing Fu,Wen Xiao, Jie Shen, Guixia Liu, Weihua   Li*, and Yun Tang*     PLoS One 2012,7,doi:10.1371/journal.pone.0033500.g001 4.092 22 Prediction   of Chemical-Protein Interactions Network with Weighted Network-Based   Inference Method Feixiong   Cheng, Yadi Zhou, Weihua Li, Guixia Liu, and Yun Tang* PLoS One 2012,7(7),doi:10.1371/journal.pone.0041064.g001 4.092 23 Insulin-like   Growth Factor-1 Receptor (IGF-1R) Kinase Inhibitors in Cancer Therapy:   Advances and Perspectives Mengzhu   Xue, Xianwen Cao, Ye Zhong, Dong Kuang, Xiaofeng Liu, Zhenjiang Zhao, and   Honglin Li* Curr. Pharm. Design 2012,18(20),2901-2913 3.87 24 The   Effect of First-in-Class Small Molecule RhoA Inhibitor, HL07, on the   Phenylephrine-induced Artery Contraction Yan   Zhang, Jing Deng, Sheng Ma, Lin Xue, Jin Zhu, Weiliang Zhu, Hualiang Jiang,   Jian Li*, and Liyan Miao* Curr. Pharm. Design 2012,18(27),4258-4264 3.87 25 MiR-222   modulates multidrug resistance in human colorectal carcinoma by   down-regulating ADAM-17 Ke   Xu, Xin Liang, Ke Shen, Liyun Sun, Daling Cui, Yuxia Zhao, Jianhui Tian*, Lei   Ni*, and Jianwen Liu* Exp. Cell Res. 2012,318(17),2168-2177 3.58 26 Prediction   of chemical–protein interactions: multitarget-QSAR versus computational   chemogenomic methods Feixiong   Cheng, Yadi Zhou, Jie Li, Weihua Li, Guixia Liu, and Yun Tang*  Mol. BioSyst. 2012, 8, 2373–2384 3.534 27 Altered   let-7 expression in Myasthenia gravis and let-7c mediated regulation of IL-10   by directly targeting IL-10 in Jurkat cells Lin   Jiang, Zhuoan Cheng, Shaobo Qiu, Wenjing Bao, Chao Jiang, Fangyuan Zou, Ping   Liu*, and Jianwen Liu* Int. Immunopharmacol. 2012,14(2),217-223 2.376 28 Preparation,   characterization and pharmacokinetic studies of   tacrolimus-dimethyl-beta-cyclodextrin inclusion complex-loaded albumin   nanoparticles Shanshan   Gao, Jun Sun, Dongjun Fu, Hongli Zhao, Minbo Lan, and Feng Gao* Int. J. Pharm. 2012,427(2),410-416 3.35 29 Discovery   and structureeactivity analysis of selective estrogen receptor modulators via   similarity-based virtual screening Jie   Shen , Jing Jiang , Guanglin Kuang, Chengfang Tan, Guixia Liu, Jin Huang *,   and Yun Tang* Euro. J. Med. Chem. 2012, 544, 188-196 3.346 30 Oxo-Heterocyclic   Fused Naphthalimides as Antitumor Agents: Synthesis and Biological Evaluation Shaoying   Tan, Hong Yin, Zhuo Chen, Xuhong Qian, and Yufang Xu Euro. J. Med. Chem. 2013,DOI:10.1016/j.ejmech.2012.12.039 3.346 31 MiR-320a   is Downregulated in Patients with Myasthenia Gravis and Modulates   Inflammatory Cytokines Production by Targeting Mitogen-activated Protein   Kinase 1 Zhuoan   Cheng, Shaobo Qiu, Lin Jiang, Anle Zhang, Wenjing Bao, Ping Liu, and Jianwen   Liu J. Clin. Immunol. 2012,DOI:10.1007/s10875-012-9834-5 3.077 32 Facile   and highly diastereoselective synthesis of 3-aminooxindoles via   AgOAc-catalyzed vinylogous Mannich reaction Yuhua   Shi, Zheng Wang, Ying Shi, and Weiping Deng* Tetrahedron 2012,68(18),3649-3653 3.025 33 NHCs-mediated   benzoates formation directly from aromatic aldehydes and alkyl halides Yi   Li, Wenting Du,* and Weiping Deng* Tetrahedron 2012,68(68),3611-3615 3.025 34 A   fluorimetric assay for human reticulocyte 15-lipoxygenase-1 activity Weiqiang   Lu, Xue Zhao, Shien Zou, and Jin Huang* Anal. Biochem. 2012,426(1),66-68 2.996 35 Natural   products as a gold mine for selective matrix metalloproteinases inhibitors Liyan   Wang, Xi Li, Shoude Zhang, Weiqiang Lu, Sha Liao, Xiaofeng Liu, Lei Shan, Xu   Shen, Hualiang Jiang, Weidong Zhang*, Jin Huang*, and Honglin Li* Bioorg. Med. Chem. 2012,20(13),4164-4171 2.921 36 Glass   carbon electrode modified with horseradish peroxidase immobilized on   partially reduced graphene oxide for detecting phenolic compounds Yan   Zhang, Jiali Zhang, Haixia Wu, Shouwu Guo, and Jingyan Zhang J. Electroanal. Chem. 2012,68,49-55 2.905 37 HDAC   inhibitor DWP0016 activates p53 transcription and acetylation to inhibit cell   growth in U251 glioblastoma cells Hui   Jin, Lei Liang, Lifeng Liu, Weiping Deng, and Jianwen Liu* J Cell Biochem. 2013,DOI:10.1002/jcb.24491 2.868 38 7b,   a novel amonafide analog, inhibited proliferation and phorbol 12-myristate   13-acetate/phytohemagglutinin-induced inflammatory responses of Jurkat T   cells via p73-dependent pathway and decrease of nuclear factor-kappaB   DNA-binding, respectively Jin   Shao, Yiquan Li, Ke Shen, Bing Lin, Yufang Xu, Yanhua Lu, Peihao Yin, Qi Li ,   Jianwen Liu, and Xuhong Qian Leukemia Lymphoma 2013,54(2),359-371 2.58 39 Discovery   of di-indolinone as a novel scaffold for protein tyrosine phosphatase 1B   inhibitors Houling   Dai, Lixin Gao, Ying Yang, Jingya Li, Jiagao Cheng, Jia Li , Ren Wen, Yanqing   Peng, and Jianbin Zheng* Bioorg. Med. Chem.   Lett. 2012,22(24),7440–7443 2.554 40 Discovery   of new non-steroidal FXR ligands via a virtual screening workflow based on   Phase shape and induced fit docking Jing   Fu, Pei Si, Mingyue Zheng, Lili Chen*, Xu Shen, Yun Tang, and Weihua Li* Bioorg. Med. Chem.   Lett. 2012, 22, 6848-6853 2.554 41 Synthesis,   structure-activity relationship and pharmacophore modeling studies of   pyrazole-3-carbohydrazone derivatives as dipeptidyl peptidase IV inhibitors Deyan   Wu,  Fangfang Jin, Weiqiang Lu,  Jin Zhu, Cui Li, Wei Wang, Xu Shen, Yun   Tang, Hualiang Jiang, Jin Huang*, Guixia Liu*, Jian Li* Chem. Biol. Drug Des. 2012, 79, 897-906 2.527 42  Neuroprotective effects of bacopaside I in   ischemic brain injury Xiaojun   Liu, Rongcai Yue, Jigang Zhang, Lei Shan, Rui Wang, and Weidong Zhang Restor. Neurol   Neuros. 2012，DOI:10.3233/RNN-120228 2.5 43 1-(2,6-Dibenzyloxybenzoyl)-3-(9H-fluoren-9-yl)-urea:   a novel cyclophilin A allosteric activator Maosheng   Lv, Ting Shi, Xiaona Mao, Xi Li , Yingyi Chen, Jin Zhu, Shuaishuai Ni , Xu   Shen, Hualiang Jiang, Jian Li, Jian Zhang*, and Jin Huang* Biochem. Biophys.   Res. Commun. 2012,425(4),938-943 2.484 44 Dilithium   Tetrachlorocuprate(II) Catalyzed Oxidative Homocoupling of Functionalized   Grignard Reagents Sikai   Hua, Qiupeng Hu, Jiangmeng Ren*, and Bubing Zeng* Synthesis 2013, DOI:   10.1055/s-0032-1316841 2.466 45 Pharmacophore,   3D-QSAR and Bayesian Model Analysis for Ligands Binding at the Benzodiazepine   Site of GABA(A) Receptors: the Key Roles of Amino Group and Hydrophobic Sites Ying   Yang, Wei Zhang, Jiagao Cheng,*, Yun Tang, Yanqing Peng , Zhong Li,* Chem. Biol. Drug Des. 2012,DOI:10.1111/cbdd.12100 2.282 46 Synthesis,   Structure–Activity Relationship, and Pharmacophore Modeling Studies of   Pyrazole-3-Carbohydrazone Derivatives as Dipeptidyl Peptidase IV Inhibitors Deyan   Wu, Fangfang Jin, Weiqiang Lu, Jin Zhu, Cui Li, Wei Wang, Yun Tang, Hualiang   Jiang, Jin Huang*, Guixia Liu*, and Jian Li* Chem. Biol. Drug Des. 2012, 79, 897–906 2.282 47 The   concise cue-AAC ligation remarkably enhances the corrosion inhibitive potency   of natural amino acids for mild steel in HCl Qiong   Deng, Xiaopeng He*, Hongwei Shi, Baoqin Chen, Guixia Liu*, Yun Tang, Yitao   Long, Guorong Chen*, Kaixian Chen Ind. Eng. Chem. Res. 2012, 51, 7160-7169 2.237 48 The   protection of acetylcholinesterase inhibitor on β-amyloid-induced the injury   of neurite outgrowth via regulating axon guidance related genes expression in   neuronal cells.   Jiaoning   Shen, Dengshun Wang, and Rui Wang Int. J. Clin. Exp.   Pathol. 2012,5(9),900-913     1.893 49 Bioactive   phenolics and terpenoids from Manglietia insignis Shanzhai   Shang, Lingmei Kong, Liping Yang, Jing Jiang, Jin Huang, Haibo Zhang, Yiming   Shi, Wei Zhao, Honglin Li, Huairong Luo, Yan Li , Weilie Xiao*, and Handong   Sun* Fitoterapia 2013,84,58-63 1.84 50 Identification   of diverse dipeptidyl peptidase IV Inhibitors via structure-based virtual   screening Cui   Li, Weiqiang Lu, Chunhua Lu, Wen Xiao, Xu Shen, Jin Huang*, Guixia Liu*, and   Yun Tang J. Mol. Model. 2012, 18, 4033-4042 1.797 51 Identification   of old drugs as potential inhibitors of HIV-1 integrase – human LEDGF/p75   interaction via molecular docking Guoping   Hu,  Xi Li , Xianqiang Sun, Weiqiang   Lu, Guixia Liu, Jin Huang, Xu Shen, and Yun Tang* J. Mol. Model. 2012, 18, 4995-5005 1.797 52 In   silico investigation of interactions between human cannabinoid receptor-1 and   its antagonists Guanglin   Kuang, Guoping Hu, Xianqiang Sun, Weihua Li, Guixia Liu, and Yun Tang* J. Mol. Model.  2012, 18, 3831–3845 1.797 53 Synthesis,   activity evaluation, and docking analysis of barbituric acid aryl hydrazone   derivatives as RSK2 inhibitors Mengzhu   Xue, Minghao Xu, Weiqiang Lu, Jin Huang, Honglin Li, Yufang Xu, Xiaofeng   Liu*, and Zhenjiang Zhao J. Enzyme Inhib. Med.   Chem. 2012,DOI:10.3109/14756366.2012.681651 1.617 54 Determination   of aristolochic acids in rat serum by high performance liquid   chromatography-Q-TOF tandem mass spectrometry Jiangping   Gu, Pinjie Zhang, Feifang Zhang*, HeQing Shen, Bingcheng Yang*, Xinmiao   Liang, and Xiaogang Chu Anal. Methods-UK 2013,DOI:10.1039/c2ay25860a 1.547 55 The   role of benzoic acid in proline-catalyzed asymmetric Michael addition: a   density functional theory study Hongwei   Shi, Xiangui Huang, Guixia Liu*, Kunqian Yu, Congying Xu, Weihua Li, Bubing   Zeng*, and Yun Tang* Int. J. Quantum Chem. 2012, in press   (published online: July 20, 2012, DOI: 10.1002/qua.24297) 1.357 56 Comparative   pharmacophore modeling of human adenosine receptor A1 and A3 antagonists  Zhejun   Xu, Feixiong Cheng, Li Jie, Yadi Zhou, Su Ni, Weihua Li, Guuixia Liu, and Yun   Tang* Sci. China Chem.  2012, 55, 2407-2418 1.02 57 Argutalactone,   an Unprecedented Sesquiterpenoid Lactone with a 6/5/7 Tricyclic System from   Incarvillea arguta. Jianjun   Fu, Liyan Wang, Honglin Li, Jiangjiang Qin, Yunheng Shen, JiaGao Cheng, Huizi   Jin*, and Weidong Zhang*  J. Asian Nat. Prod.   Res. 2012, 14, 496–502. 0.944 58 Kinetic   Resolution of Aryl Alkenylcarbinols Catalyzed by Fc-PIP Bin   Hu, Meng Meng, Shanshan Jiang, and Weiping Deng* Chin. J. Chem.  2012,30(6),1289-1294 0.775 59 Facile   Synthesis of 4,5-Disubstituted 2H-1,2,3-Triazoles by Catalyst-free   Cycloaddition between Substituted Vinyl Sulfones and Sodium Azide under   Ambient Conditions Jinjin   Yang, Wei Yin, Renhua Liu, and Changhu Chu* Chin. J. Chem.  2012,30(12),2786-2790 0.755 60 Highly   Substituted Cyclopentenes Formation via a Stereoselective Tandem CDC Reaction   and Cyclization Yi   Li, Li Cao, Xiaoyan Luo, and Weiping Deng* Chin. J. Chem.  2012,30(12),2834-2838 0.755 61 Inhibitors   of HIV-1 integrase - human LEDGF/p75 interaction identified from natural   products via virtual screening  Guoping   Hu, Xi Li, Yaozong Li, Xianqiang Sun, Guixia Liu, Weihua Li, Jin Huang*, Xu   Shen, and Yun Tang* Chin. J. Chem.  2012, 30, 2752-2758  0.755 62 A   highly efficient BF3·Et2O-catalysed intramolecular [3+2] cycloaddition for   the synthesis of 3,4-dihydrobenzopyrano[3,4-c]pyrazoles Weiliang   Wang, Yulan Feng, Wenqiang Gao, Xiaoyan Luo, and Weiping Deng* RSC Advances 2013,DOI:10.1039/c2ra22025c 63 Novel   inhibitors for p90 ribosomal S6 protein kinase 2: design, synthesis and SAR Mengzhu   Xue, Jun Yang, Bin Wu, Xue Zhao, Xiaofeng Liu, Jin Huang, Zhenjiang Zhao*,   Honglin Li*, and Yufang Xu Journal of Chinese   Pharmaceutical Sciences 2012,21(5),401-408 64 Curative   effect of novel oral carbon microspheres on streptozotocin-induced diabetes   mellitus in rats Qing   Shen, Shanshan Gao, Yini Xie, Licheng Ling, and Feng Gao* Journal of Chinese   Pharmaceutical Sciences 2012,21,234–241 65 Discovery   and early evaluation of new chemical entities Jing   Deng, Fei Zhao, Jian Li, Hong Liu , and Hualiang Jiang* Journal of Chinese   Pharmaceutical Sciences 2012,21(5),369-384 66 Synthesis   and biological evaluation of noscapine analogues as microtubule-interfering   agents Houling   Dai, Jianbin Zheng*, Min Lin, Jing Zheng, Fusheng Zhou, Xiaochun Dong, Lei   Guo, Jianwen Liu, and Ren Wen Acta Pharmaceutica   Sinica 2012,47(10),1347−1357